Bioreactor Analysis and Design

Module Notes
Faculty Member (Members):
Undergraduate, 9th Semester (5th Year, Fall)
Module Category: Thematic Unit Electives, Group A
Module Type: Core Chemical Engineering
Teaching Language: Greek
Course Code: CHM_E_A3
Credits: 3
ECTS Credits: 4
Teaching Type: Lectures (3h/W) Project/Homework (10/Semester)
Module Availability on Erasmus Students: No
Course URL: E-Class (CMNG2192)
Module Details

Application of knowledge of basic biology, reaction engineering and biokinetics in designing and analyzing systems of bioreactors.

Application of mathematical and computational methods of analyzing and solving systems of differential equations representing mathematical models of bioreactors.

Constuction and computational analysis of mathematical models of systems of bioreactors.

Knowledge of basic biology, principles of bioengineering, reaction engineering, mathematical and computational methods of analyzing and solving systems of differential equations.

BIOREACTORS. Chemostat, Monod’s model in the chemostat. Product formation. Maintenance and endogenous metabolism. Non-ideal bioreactors. Cell attachment to chemostat walls.

DYNAMIC BEHAVIOR OF BIOREACTORS. Elements of system dynamics. Dynamic behavior of the chemostat. Monod’s model. Andrews’s model.

LIMITATION OF THE MICROBIAL GROWTH RATE FROM MULTIPLE NUTRIENTS. Classification of pairs of nutrients. Complementary nutrients. Substitutable nutrients. Generalized models of microbial growth.

DISTRIBUTED MODELS. Population balance of particles. Breakage process. Aggregation process. Balance of environmental components. Cell population balance in a chemostat.

MIXED CULTURES OF MICROORGANISMS. Classification of microbial interactions. Direct microbial interactions. Indirect microbial interactions. Combinations of interactions.

Teaching Organization

LECTURES: 3 h/w
PROJECT/HOMEWORK: 10/semester

 

Total Module Workload (ECTS Standards):

109 Hours

Homework sets 20%

Final exam 80%

1.  Σ. Παύλου, Μαθηματικά μοντέλα μικροβιακής ανάπτυξης σε βιοαντιδραστήρες, Εκδόσεις Πανεπιστημίου Πατρών

2. Γ. Λυμπεράτος, Σ. Παύλου, Εισαγωγή στη Βιοχημική Μηχανική, Επιστημονικές Εκδόσεις Τζιόλα (2010)