Module Notes
Faculty Member (Members):
Undergraduate, 9th Semester (5th Year, Fall)
Module Category: Thematic Unit Electives, Group C
Module Type: Core Chemical Engineering
Teaching Language: Greek
Course Code: CHM_E_Γ3
Credits: 3
ECTS Credits: 4
Teaching Type: Lectures (3h/W) Project/Homework (1/Semester)
Module Availability on Erasmus Students: No
Course URL: E-Class (CMNG2117)
Module Details

The meanings of biocompatibility and toxicity of biomaterials.

The different types of biomaterials depending on the biomedical application and the most important mechanical, physicochemical and biological properties of these materials.

The most important mechanisms of cells response to wounds caused by biomaterials implantation.

The most important in-vitro and in-vivo test of biomaterials for monitoring their biocompatibility and toxicity.

The most important mechanisms of cells response to wounds caused by biomaterials implantation.

The most important types of biomaterials infection and prevention methods.

The main methods and techniques for drug delivery control and targeting.

There are no prerequisite modules. It is, however, recommended that students should have basic knowledge of Materials Science, Polymers Science and Biology

A. Introduction to biomaterials and biocompatibility / toxicity. 1st, 2nd and 3d generation biomaterials. Replacement, Reconstruction and regeneration of basic organs

B. Types of biomaterials: Synthesis and properties of metallic, ceramic and polymeric biomaterials Mechanical and physicochemical properties . Hydrogels, Natural Biomaterials, medical fibers and textiles.

C. Methods for surface modification of biomaterials.

D. Proteins – Cells – Tissues: Mechanisms of interactions with biomaterial surfaces. Cells and tissue responses to implantation wounds

E. Biomaterials Infection. Main types and prevention methods

F. Biomaterials for drug delivery applications

G. FDA approvals and CE marking rules and classifications of biomaterials

Teaching Organization

PROJECT / HOMEWORK: 1/semester

Total Module Workload (ECTS Standards):

100 Hours

  1. One project per group of one or two students in a specific biomaterials topic (50 % of final grade). The students presents their project and deliver a 10 pages summary of the project
  2. Final written exams (50 % of final grade)

1. Biomaterials Science: An Introduction to Materials in Medicine, Second Edition [electronic resource] - 2nd edition/2004 - Author: Ratner, B. D.- ISBN: 978-0125824637, Type: Electronic book

2. Biomaterials [electronic resource], Authors: Park, Joon and Lakes, R.S., ISBN: 9780387378800, Type: Electronic book

3. Biomaterials The Intersection of Biology and Materials Science, J. S. Temenoff, A. G. Mikos ISBN 978-0-13-009710-1